You might eek out another few thousand km's by taking a link out, but the failure method becomes more and more likely to be a snapped chain. I'd consider I'd had good value from it. flip both chainring and sprocket and fit the new chain.
Agree. After 22000 km and given the wear on the chainring, time for a new chain and flip the sprocket and chainring.
Snapping a chain could be very inconvenient.
On a hub gear bike I have had this happen once, the outer plates on one link failed on a very worn chain, but nothing like 22000 kms use. This was before I started using Chaingliders, which make a significant difference to transmission maintenance and longevity, at least for all-weather use in the coastal area where I live.
Fortunately for me I was only a few kms from home and the bike trailer I was towing had been unloaded before the chain broke. So not too hard to push the bike/trailer up the hills and coast on the downhills. My bike toolkit now includes spare 1/8" chain links in addition to the 3/32" quick links and spare links I already had.