It worked for me on a Brompton, where for several years I used a double chainring with a 5-speed Sturmey hub to extend the gear range.
No real difference if using a Rohloff, or an Alfine 8 as PH has done.
I have the Rohloff on my Raven Sport Tour geared quite low - 42 x19, which gives a range of 15" to 80" with my tyres. I don't (yet) really need the lowest gear on this bike, 15" gives about 4.4 km/h at a "lazy" cadence of 60 rpm, so about walking speed.
And I could do without the highest gear, which gives 35 km/h at my usual cadence of 90 rpm, not a speed I can maintain on the flat for long. Though I have pedalled that bike up to 50 km/h on a gentle downhill just to see if I could do it (130 rpm, again not sustainable for long periods)
On my heavy tourer, I gear even lower at 13" to 67". My reasoning is that I sometimes use the very low gear when really tired at the end of a long day, and I wont need to (or be able to) go very fast with a full touring load. 67" is about 29 km/h at 90 rpm.
I don't usually "spin out" on downhills, I just stop pedalling and save my energy for the next uphill.
But if someone does need more range than the Rohloff's 526%, a double chainring should work quite well.