I wear photochromatic lenses all the time, even indoors. All my glasses, except my cycling glasses are are photochromatic. But a couple of years ago I got tired of the wind blowing around my specs and making my eyes water, and since I was having my eyes tested anyway, I looked into various wraparound options and even over the glasses ski goggles, though I found those overkill and prone to misting.
I was shocked at the silly prices of cycling wear from the main brands. Screw them. I told my optician to go find me a good value German brand made obsessives, of the same quality as the thirty-year old Menrad gold frames that will see me out. It turned out he had what I wanted already:
https://shop.b-s.de/shop_html and search for "8918" without the quotation marks, then, when you see a colourful page, click the British flag top left to get English. This is the extras page; what is in the basic kit may differ from country to country, but all the available bits are on this page
What I have is the model 8918, which comes with the prescription insert to be glazed, and three sets of outer lenses. I also ordered a spare complete frame with all fittings, extra spare nosepiece, and all the available outer lenses not in the kit, including the special polarising lens; the lenses are amazingly cheap when they don't carry a cycling fashion name. Together with an eye test and real glass prescription lenses to the Rx insert, the whole lot came to EURO 115. You can't even buy a pair of cheap Oakleys for that! And these Breitfeld & Schlickert frames and lenses are of excellent design and workmanship. Each set comes in a zip case with space for three sets of wraparound lenses, plus cloth case for your bike that also doubles as a cleaning cloth.
As it happened, since I got these glasses, the weather has been poor, so I've only used the polarising and grey and brown lenses a few times, but the orange and yellow shooter's lenses have seen a lot of use; I now don't leave the house without my wraparounds even if walking rather than cycling. I ordered a set of clear lenses for nighttime use but found them surplus to requirements: the shooter's yellow lenses are brilliant for riding at night. Incidentally, after my optician talked to the local importer about what I was trying to do, we were told we could swap the coloured extra lenses around without extra cost except for the polarising lens (10 euro, cheep); but the coloured lenses were so cheap, I couldn't be bothered and just stuck to two sets of everything.
These frames and the outers lenses will last me thirty years or more; the inserts can be reglazed with new prescriptions. I'm well pleased with my investment. If I had bought only one set, and not ordered all the extras, together with the Rx glazing it would have come to 55 euro, I seem to remember; where I live that is stunningly cheap. I spent the extra gladly, because I was buying into a system, and nothing is more irritating than finding it has been discontinued when you want to expand the bits you have, or having to scrap hardly used extras because you can't replace the main item (the frame and Rx insert and machined nosepiece combo).
Look carefully at the piccie and you'll see the prescription insert lurking behind the polycarbonate wraparound:

Very comfortable specs, I should add.