True but cartridge's have made it easier to change the pads
If you are able to extract the pads from the cartridge after they are used up and brake dust, aluminum oxide and rubber have been welded with each other. It's already difficult to squeeze them in, i've never been able to extract them without excessive force, often only with the help of a sharp edge or a screwdriver(After removing the adapter from the brake arm) - and i've been using cartridge-adapters from different brands since 7 years. And positioning the pads is still cumbersome, although a lot better than with cantilever(I remember spending dozens of minutes of positioning on a pair of those). I'm also fed up with bowden wire, you will inevitably loose slipperiness after a while. Two years ago i tried Nokon but didn't experience much difference, besides they start squeaking due to oxide accumulating between the aluminium beads.
Pure "brake performance" is not a decision maker for me, as all brakes i've used in the last years had more than enough power to block the wheels with little force needed on the lever. I've read both XTR and HS33 are superior in terms of sensibility though.
Thanks for your comments on Iran/Pakistan, looking forward to this travel since years :-) I was wondering if it's possible to cross the border near the makran coast, though the crossing at Pishin(Iran) doesn't seem to be open for foreigners.