Schwalbe Marathon+ are a lot like Rohloff hubs - heavy, expensive, and last a very long time. I have one on the rear with almost 20,000 miles on it (and about ready to be replaced) but probably no more than 2-3 flats in that time. Not a good long distance road tire, but for city commuting they are the best that I know of.
I won't be getting anything like that mileage from my Marathon Supreme tyres. So far, I have only scrapped 2, with an average of 10,000 kms (about 6,000 miles). Both of these were from carcass failures on the rear wheel. I swap the front tyre to the back when I wear out or scrap the rear tyre, so I don't have different values for front and rear tyres.
IMO, still good value for money from a lightweight tyre used hard for a mixture of utility cycling, cycle camping on road, with some off-road use on rocky and sandy tracks.
Punctures with Supremes- IIRC about 3 in 23,000 kms of use in the 50 mm width size, but rare enough that I don't really notice. Compared to none at all with Marathon Plus in about 9,000 kms of use (all sizes).
For my own use, I prefer spending 20-30 minutes sorting out a puncture every 5-6 thousand kms to losing 1 to 2 km/h of speed and having a harsher ride with a (nearly) puncture proof tyre.
But I am lucky to live in an area with relatively clean and well-maintained roads with not too much glass or metal debris. No goat-head thorns either, although blackthorn caused enough punctures to make me change from lightweight Brompton Yellow to heavier Schwalbe Marathon (not plus) tyres when I was working on survey contracts with my Brompton.