Indexed shifters have been around for 20+ years, and work very well for the rear derailleur, and OK for a front triple. (They are pretty irrelevant for a front dual derailleur.)
The main disadvantage is that most of them have no ability to trim the front mech to avoid chain rub. (Honourable exception is Campag ergo before the latest models.) If everything is adjusted correctly, and you avoid silly gear combinations, this is not usually a problem, but in the real world, it would be handy.
I've got bikes with drop bar Shimano sti, down-tube and under-bar pods, and I can get along with all of them. I've also used Compag ergos and bar-end shifters, but not so much. As far as shifting performance goes, I prefer the mountain bike style under bar pods, but they don't go too well with drop bars.
For a dedicated, long term tourer, I'd probably get a Rohloff hub, but if I was using derailleurs and drop bars, I'd go for down-tube shifters for simplicity and robustness. I've had my sti system knocked out of adjustment in transit on aircraft, and significant damage could easily leave you unable to change gears. Most down-tube or bar-end shifters will allow you to turn off the indexing so you can cope with a bent derailleur or mount. They are also a bit easier to find cables for in the wild. Separate brake levers also means you can use V brakes rather than cantilevers, and they are a bit less fiddly.
What I'd really prefer for my day-to-day use is a down-tube shifter for the front mech, and an sti for the rear. The indexed shifting between chain rings is a bit brutal, and doesn't allow for trimming. Even with a well adjusted derailleur, I occasionally throw the chain off (maybe once a year, but it happened last Sunday.) Sadly, no-one sells such a setup, and I'm not motivated enough to gut my current levers.