I've had both, having crashed the first, so can make that comparison.
No, the differences are minor and they're largely the same frame, I wouldn't change unless there was a pressing need.
Biggest difference is the EBB, it's gone from a mini to full size, so you gat a full throw of the chain and there's no longer restricted chain/sprocket choices. Maybe as a result of that , or maybe unrelated, there's a little more clearance, which I consider a plus. Possibly also tied up with that there's no longer the option of running a calliper brake on the rear. Other than that the only difference I noticed was the rear brake cable run is through loops rather than with clips, a bit of a pain fitting hydraulics but neater once done.
If there's anything else, I haven't noticed, it rides exactly the same.