Hi Zero!
A couple of data points offered in hopes they will help as a reference...
My two favorite steel-framed randonneur/Audax/touring bikes are basically standard 700C-wheeled road touring bikes. The ride characteristics of one is about 3/4 Thorn Club Tour, 1/4 Thorn Audax, full Club Tour on the other by my estimation. Both have front and rear pannier racks with pump, three bottles, mudguards, dyno lighting, and small underseat tool bag including a small multitool, patch kits and a spare tube. They weigh about 32lb/14.5kg each, dry. I weigh 172lb/78kg.
Each bike has just one set of wheels for all purposes. I built them myself. They have proven reliable and trouble-free for 28,000+ and 32,000+ miles/45,000-51,400km respectively, whether on 300-400km day rides or carrying a maximum of 56lbs/25kg on gravel and reasonably rough roads.
Except for a difference in OLN spacing between the two bikes, I used:
• 36 hole Mavic MA-2 rims (polished). 20.5mm outside width. See:
http://www.bikepro.com/products/rims/mavicroad.shtml• 36 hole DT 1.8mm/15g unbutted spokes with either DT or Wheelsmith plated brass nipples
• Laced 3x
• Phil Wood hubs (freewheel rear). I have another front wheel like this with a SON28 New dynohub instead of the Phil hub.
One bike uses Panaracer Paselas, 700x37mm (34mm actual width when mounted on the MA-2s and inflated to pressure). Baseline pressures without cargo and dry are F/R 3.2/4.0bar or 47/58psi.
The other bike uses Bontrager Select K road slicks, 700x32mm (33 actual width when mounted on the MA-2s and inflated to pressure). Baseline pressures without cargo and dry are F/R 3.5/4.3bar or 51/63psi.
Pressures are adjusted upward for water and cargo carried.
These wheels are not heavy, but they are not light; I'd call them a good midweight solution built with older components some time ago. They stay true and round and I've not broken a single spoke.
In answer to your question, I'd suggest going with a "medium" set for maximum versatility and a good balance between light weight and strength with durability being paramount.
Best,
Dan.