Hi, I think for the most part, depending on conditions and what the bike is subject to, that most things will quite happily stay where you leave them, IE: will not fall apart etc.... But loctite along with other products of similar substance can also be a great additive to lots of mechanical things which will aid in the long term serviceability of things.
I have read some accounts which relate directly to the hub screws either seizing up and snapping when removal has been attempted, or conversely falling out due to coming loose.
The hub bolts although connect both half's of the hub shell together are not under full axial load persae, but are rotational load. The two half's connect together with an internal male mating flange to which the main shell receives and locates giving that perfect fit, even with no screws fitted there is no axial movement due to the design, however there would be nothing to stop the end shell from turning and of course keeping the oil in.
One of the main advantages of loctite or similar products is the anti galling properties along with total water proofing of the threads, and what seems to be a predictable outcome with regards to later service expectations.
As Dan has also suggested, putting wet lubricants on threads also has an effect on the final figure dialled in to torque wrenches due to the very nature of the stuff, again I think the use of a torque wrench useful but i believe very much in knowing how to feel when something is tight, this can't be felt through a torque wrench very well. There is a certain point which I'm sure we have all seen at some point either when tightening or undoing a screw or bolt when you just get to the point when that certain (feel) of the bolt shearing comes and then that deep sigh and grrrr of having to remove the remnants of what's left.
With the hub we have the worst possible case, we have a soft alloy shell with steel (bright zinc plated) screws that are much harder than the shell. Once the zinc plating is compromised this allows galvanic/ electrolytic corrosion to take place which allows the screw to expand thus getting tighter, this is why screws get tight, if both mating surfaces could rust then they actually fuse together and cause much more problems. I'm sure we have all found this when working on the car underneath etc....
The problem with most screws seem to be exacerbated when they have been left for a long time and have been subject to weathering etc, I know that there is the old cliche' don't try to fix something that isn't broken, but I don't think it should be taken at literal as it sounds, sometimes by leaving some things this is actually making them worse. I'm a great believer in checking to make sure things come apart and go back together again (within reason) just from a serviceability point of view. On the other hand taking something part to many times can also have a detrimental effect. It's finding that balance and of course knowing when to leave things alone and when to have intervention.
I think in summary, from my point of view anyway and that's not to say I'm right I just go along with experience and real life situations that it wouldn't go a miss to at least check critical screws such as the hub screws (once in a while) if you feel confident to do so. Even more important and I know it's been topic for discussion on here many times that the sprocket is removed even if it goes back on the same way it wouldn't do any harm just to know it comes off. The tools that are used to remove most fasteners make such a difference in the outcome (I'm talking about the quality of the tool) with most tools the more you pay the better they will perform and last, and of course make the job more pleasurable in doing. You just get what you pay for.
All the best
Dave.