As a practical matter I'd like to lower the centre of gravity of that bike and make provision for a bit more than leg power for touring. I've calculated (guesstimated <tm>) that the bike as shown would limit me to 7% of the roads hills I ride from the Rome of West Cork, and be bloody dangerous on the downhills, utterly unstable because its centre of aerodynamic pressure would be permanently ahead of its centre of gravity.
This has more engineering and dynamic integrity. With only leg-power or a small electric motor would to cater for, it could probably be made as light a standard touring bicycle:
(http://coolmainpress.com/miscimage/Humongous%20Motorized%20Unicycle%20de%20Luxe.jpg)
Humongous Motorized Unicycle de Luxe
There is of course a reason why, in all the decades since even inventors wore a tie and polished shoes, this large version of the unicycle hasn't replaced the diamond-frame safety bicycle: it looks weird.