For experimenters with different drivetrains and other other components, the Surly Karate Monkey frame and fork were absolutely spiked with braze-ons -- actually weld-ons -- to attach very possible layout and fit-out, including some pretty bizarre. You could have both rim and disc brakes on the same wheel. I didn't actually buy a Karate Monkey frame -- it was on too short a wheelbase with too steep a geometry, very nervy, for my liking, and horrible aesthetics -- but there was no arguing with its utility.